Own goal

时间:2019-03-07 14:07:00166网络整理admin

INSULIN itself triggers the immune system to destroy insulin-producing cells in the pancreas during early-onset diabetes. Susan Wong of Yale University genetically engineered diabetes-causing T cells from mice to turn blue when activated. Exposing these cells to a soup of protein fragments from insulin-producing cells, Wong and her colleagues found that a particular region of the insulin molecule was activating the T cells (Nature Medicine, vol 5, p 1026). “It’s likely that this is what happens in humans too,